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Individual Susceptibility to Post-Spaceflight Orthostatic Intolerance
DSO 496


Overview
Susceptibility to postflight orthostatic intolerance - lightheadedness or fainting upon return to Earth - is highly individual. Some astronauts are little affected, while others have severe symptoms. Women are more often affected than men. The goal of this DSO is to discover the mechanisms responsible for these differences in order to customize countermeasure protocols.

History/Background
It has been well documented that spaceflight significantly alters cardiovascular function. One of the most important changes from a crew safety standpoint is postflight loss of orthostatic tolerance, which causes astronauts to have difficulty walking independently and induces lightheadedness or fainting. These may impair their ability to leave the orbiter after it lands.

This DSO will perform a flight-related study, designed to clarify preflight and postflight differences in susceptible and nonsusceptible astronauts. There are no on-orbit activities associated with this DSO.


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Updated: 03/01/2001

Boeing NASA United Space Alliance

Editorial/Technical Comments: ShuttlePresskit