|
Spaceflight-induced alterations in the immune response become increasingly important on long missions, particularly the potential for reactivation and dissemination (shedding) of latent viruses. An example of a latent virus is Herpes Simplex Type 1 (HSV-1), which infects 70 to 80 percent of all adults. Its classic manifestations are cold sores, pharyngitis, and tonsillitis; and it usually is acquired through contact with the saliva, skin, or mucous membranes of an infected individual. However, many recurrences are asymptomatic, resulting in shedding of the virus. Twenty subjects have been studied for Epstein-Barr virus. Three additional viruses will be examined in an expanded subject group.
|
